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Folding mode and characteristics: touch killing, stomach poisoning, strong penetration. It is a macrolide disaccharide compound,which is a natural product separated from soil microorganisms. It has contact killing and stomach poisoning effects on insects and mites. It also has weak fumigation effect and has no internal absorption effect. But it has a strong osmotic effect on leaves, kills pests under the epidermis, and has a long residual period and it does not kill eggs. Its mechanism of action is different from that of general insecticides is  that it interferes with neurophysiological activities and stimulates the release of r-aminobutyric acid,which inhibits the nerve conduction of arthropods. The mites, nymphs and insects show paralysis symptoms after contact with abamectin, which leads to inactivity and no feeding, they will die 2-4 days later. Since it does not cause rapid dehydration of insects, its lethal effect is slow. Although it has direct killing effect on predatory and parasitic natural enemies, it has little damage to beneficial insects because of the few residues on the surface of plants. It has obvious effect on root ganglion nematode.